Publications
Be sure to check out our slidecasts, which are short recorded talks about the work in the papers. It's faster than reading!
Khalil AM, Guttman M, Huarte M, Garber M, Raj A, Rivea Morales D, Thomas K, Presser A, Bernstein BE, van Oudenaarden A, Regev A, Lander ES, Rinn JL. Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression. PNAS 2009; 106: 11667-72. PDF.
Raj A, van Oudenaarden A. Single-Molecule Approaches to Stochastic Gene Expression [Review article]. Ann. Rev. Biophysics 2009; 38: 255-70. PDF.
Raj A, van Oudenaarden A. Nature, Nurture or Chance: Stochastic Gene Expression and its Consequences [Review article]. Cell 2008; 135(2): 216-226. PDF.
Raj A, van den Boogard P, Rifkin SA, van Oudenaarden A, Tyagi S. Imaging individual mRNA molecules using multiple singly labeled probes. Nature Methods 2008; 5(10): 877-879. PDF, Supplementary material, Software.
To design your own probes, visit singlemoleculefish.com.
Maamar H*, Raj A*, Dubnau D. Noise in Gene Expression Determines Cell Fate in Bacillus Subtilis. Science, 2007 Jul 23; 317(5837): 526-9 (* equal contributions). PDF, Supplementary material, Movies
- Perspective by Mettetal and van Oudenaarden.
Raj A, Peskin CS, Tranchina D, Vargas DY, Tyagi S. Stochastic mRNA Synthesis in Mammalian Cells. PLoS Biol 2006; 4(10): e309. PDF, Supplementary material
Raj A, Peskin CS. The influence of chromosome flexibility on chromosome transport during anaphase A. Proc Natl Acad Sci USA, 2006 Apr 4;103(14): 5349-54. PDF, Supplementary material
Vargas DY, Raj A, Marras SA, Kramer FR, Tyagi S. Mechanism of mRNA transport in the nucleus. Proc Natl Acad Sci USA, 2005 Nov 22;102(47): 17008-13. PDF, Supplementary material
Raj, A., T. Phan, R. P. Lin, and V. Angelopoulos, Wind survey of high-speed bulk flows and field-aligned beams in the near-Earth plasma sheet. J. Geophys. Res. 2002, 107(A12), 1419, PDF.
